Slay The Spire
I finally beat the end game of Slay The Spire with all three characters.The Poisoner (or whatever he's called--he's the middle character) was, for me, the most difficult. If you're stuck on that character, let me mention something I didn't realize until my last few runs: Blur stacks.
Blur is a card you can play where block isn't removed at the start of your turn. If you have a 20-25 card deck with 3-4 Blur cards, and you also pick up a few Dexterity cards and upgrade them, you can wind up with 50-60 block per turn, and when an enemy doesn't attack, you'll stack that block for the next turn.
It's incredibly powerful, and you need that kind of blocking power when you face both the two on one battle and the final boss.
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