Monday, February 05, 2007

Your E-mail and Links

Excellent e-mail, as always.

Skip Key e-mailed me in reference to the nicotine hand-gel story a few weeks ago and mentioned that he'd been at a trade show where nicotine hand wipes were on display. They were being marketed to casinos for use in their poker rooms (the ones that don't allow smoking) to help keep players at the table.

E-mailer my wife let me know that she'd gotten spam from "The Stiffmister."

Chris Meyer sent me a link to a site with some pictures of the largest open pit in the world--a mine near Smirny, Russia. The pictures are amazing and you can see them here.

Rob Clendenin sent in a link to an excellent article about John Stapp that is more in-depth than the Wikipedia entry. You can read it here.

Ian Dorsch confirmed my suspicions about Square possibly licensing the Unreal 3 engine to facilitate porting between the PS3 and the 360. He sent me link to a page from the Unreal Technology website:
Unreal Engine 3 is provided as one unified codebase that compiles on PC and all supported next-generation console platforms. All game content and data files are compatible across all supported platforms, for fast turnaround time between code and content development on PC, and playtesting on console or PC.

Lastly, Brian Meyer sent me a link to a story about the DCA molecule, which holds hope as an effective treatment against certain kinds of cancers. Here's an excerpt:
Michelakis and his colleagues found that DCA normalized the mitochondrial function in many cancers, showing that their function was actively suppressed by the cancer but was not permanently damaged by it.

More importantly, they found that the normalization of mitochondrial function resulted in a significant decrease in tumor growth both in test tubes and in animal models. Also, they noted that DCA, unlike most currently used chemotherapies, did not have any effects on normal, non-cancerous tissues.

..."I think DCA can be selective for cancer because it attacks a fundamental process in cancer development that is unique to cancer cells," Michelakis said. "Cancer cells actively suppress their mitochondria, which alters their metabolism, and this appears to offer cancer cells a significant advantage in growth compared to normal cells, as well as protection from many standard chemotherapies. Because mitochondria regulate cell death - or apoptosis - cancer cells can thus achieve resistance to apoptosis, and this appears to be reversed by DCA."

"One of the really exciting things about this compound is that it might be able to treat many different forms of cancer, because all forms of cancer suppress mitochondrial function...

It's an intriguing story, and you can read it here.

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